SCHEMBL14217261

SCHEMBL14217261

CCOCC(=O)NC(CCCCNC(=O)CC)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.47
C3AR1 Q16581 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
FOLH1 Q04609 1/20 0.44
NOD1 Q9Y239 4/20 0.43
EPHX2 P34913 1/20 0.41
ALB P02768 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14998098 1.00 GLP1R (0.47) GLP1RC3AR1MEN1KMT2AFOLH1
SCHEMBL14217386 0.93 GLP1R (0.53) GLP1RC3AR1MEN1KMT2AFOLH1
SCHEMBL14238768 0.89 GLP1R (0.46) GLP1RC3AR1FOLH1NOD1EPHX2
SCHEMBL14998100 0.89 GLP1R (0.46) GLP1RC3AR1FOLH1NOD1EPHX2
SCHEMBL14217286 0.89 GLP1R (0.53) GLP1RC3AR1MEN1KMT2AFOLH1
SCHEMBL16478795 0.89 GLP1R (0.46) GLP1RC3AR1FOLH1NOD1EPHX2
SCHEMBL14217277 0.87 GLP1R (0.57) GLP1RC3AR1MEN1KMT2AFOLH1
SCHEMBL19261031 0.87 GLP1R (0.47) GLP1RC3AR1FOLH1NOD1EPHX2
SCHEMBL16472579 0.87 GLP1R (0.52) GLP1RC3AR1MEN1KMT2AFOLH1
SCHEMBL14477502 0.87 GLP1R (0.57) GLP1RC3AR1MEN1KMT2AFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9695226-B2 Growth hormones with prolonged in-vivo efficacy NOVO NORDISK HEALTHCARE AG (CH) 2017-07-04 US disclosed
US-9234192-B2 Conjugated proteins NOVO NORDISK A/S (DK) 2016-01-12 US disclosed
US-8779109-B2 Growth hormones with prolonged in-vivo efficacy NOVO NORDISK HEALTH CARE AG (CH) 2014-07-15 US disclosed
US-20140107324-A1 Growth Hormones with Prolonged In-Vivo Efficacy NOVO NORDISK HEALTH CARE AG (CH) 2014-04-17 US disclosed
US-20130004524-A1 Conjugated Proteins NOVO NORDISK A/S (DK) 2013-01-03 US disclosed
US-20120309944-A1 Growth Hormones With Prolonged In-Vivo Efficacy NOVO NORDISK HEALTH CARE AG (CH) 2012-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309944-A1 Growth Hormones With Prolonged In-Vivo Efficacy GHRHR, SHBG, GHSR GLP1R 99/4885C3AR1 1465/4885MEN1 335/4885
US-20130004524-A1 Conjugated Proteins F13B, F5, F13A1 GLP1R 4647/4885C3AR1 82/4885MEN1 3653/4885
US-20140107324-A1 Growth Hormones with Prolonged In-Vivo Efficacy SHBG, GHRHR, GHITM GLP1R 101/4885C3AR1 1771/4885MEN1 335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.