Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.51 |
| ▸ | L3MBTL3 | Q96JM7 | 10/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.44 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.44 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840531 | 0.90 | SPHK1 (0.60) | SPHK1L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL22144419 | 0.86 | KDM4E (0.49) | SPHK1L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL19567594 | 0.84 | USP2 (0.51) | L3MBTL3L3MBTL1MBTD1TP53BP1MAOA | |
| SCHEMBL22856413 | 0.83 | MAOA (0.47) | L3MBTL3L3MBTL1MBTD1TP53BP1MAOA | |
| SCHEMBL8730118 | 0.83 | L3MBTL3 (0.44) | SPHK1L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL25833691 | 0.81 | MAOB (0.52) | L3MBTL3L3MBTL1MBTD1TP53BP1MAOA | |
| SCHEMBL28853366 | 0.80 | L3MBTL3 (0.42) | SPHK1L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL14393584 | 0.80 | HTR2A (0.48) | SPHK1L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL27249154 | 0.80 | CHKA (0.51) | L3MBTL3L3MBTL1MGLLS1PR1HTR7 | |
| SCHEMBL8349588 | 0.80 | CHKA (0.51) | L3MBTL3L3MBTL1MBTD1TP53BP1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120309760-A1 | PIPERAZINE COMPOUND HAVING A PGDS INHIBITORY EFFECT | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2012-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309760-A1 | PIPERAZINE COMPOUND HAVING A PGDS INHIBITORY EFFECT | GRIK5, GRK5, KCNJ5 | SPHK1 1071/4885L3MBTL3 4147/4885L3MBTL1 3806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.