Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 10/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.44 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.44 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25833691 | 0.88 | MAOB (0.52) | MAOAMAOBL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL13169263 | 0.86 | KDM4E (0.49) | L3MBTL3L3MBTL1MBTD1TP53BP1MEN1 | |
| SCHEMBL25109335 | 0.85 | MAOA (0.43) | MAOAMAOBL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL19567594 | 0.84 | USP2 (0.51) | MAOAMAOBL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL23568275 | 0.84 | MAOA (0.43) | MAOAMAOBL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL14217337 | 0.83 | SPHK1 (0.51) | MAOAMAOBL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL23560476 | 0.82 | MAOB (0.47) | MAOAMAOBL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL24359662 | 0.82 | ADRA1A (0.45) | — | |
| SCHEMBL26912417 | 0.82 | SLC6A2 (0.41) | MAOAMAOBL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL149713 | 0.80 | ADRB1 (0.50) | L3MBTL3L3MBTL1MEN1KMT2ACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020264490-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |