Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311296 | 0.76 | GABRA1 (0.34) | GABRA1GABRA5GABRA2GABRB2GABRG2 | |
| SCHEMBL7725912 | 0.76 | GABRA1 (0.53) | GABRA1GABRA5GABRA2GABRB2GABRG2 | |
| SCHEMBL7312843 | 0.71 | IDO1 (0.47) | GABRA1GABRA5GABRA2GABRB2GABRG2 | |
| SCHEMBL14217644 | 0.69 | GABRA1 (0.60) | GABRA1GABRA5GABRA2GABRB2GABRG2 | |
| SCHEMBL5178956 | 0.68 | OPRK1 (0.49) | GABRA1GABRA5GABRA2GABRB2GABRG2 | |
| SCHEMBL2841206 | 0.68 | GABRA1 (0.49) | GABRA1GABRA5GABRA2GABRB2GABRG2 | |
| SCHEMBL7317220 | 0.68 | OPRK1 (0.38) | GABRA1GABRA5GABRA2GABRB2GABRG2 | |
| SCHEMBL11841565 | 0.66 | BRD4 (0.38) | GABRA1GABRA5GABRA2GABRB2GABRG2 | |
| SCHEMBL2843160 | 0.65 | GABRA1 (0.54) | GABRA1GABRA5GABRA2GABRB2GABRG2 | |
| SCHEMBL7724624 | 0.65 | CYP1A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE47475-E1 | Selective agents for pain suppression | WISYS TECHNOLOGY FOUNDATION, INC. (US) | 2019-07-02 | — | — | US | disclosed |
| US-8835424-B2 | Selective agents for pain suppression | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-09-16 | — | — | US | disclosed |
| EP-1925614-A1 | Anxiolytic agents with reduced sedative and ataxic effects | Wisys Technology Foundation, Inc. (US) | 2008-05-28 | — | — | EP | disclosed |