Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 9/20 | 0.60 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.60 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.60 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.60 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.60 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.60 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.60 |
| ▸ | CCKBR | P32239 | 1/20 | 0.54 |
| ▸ | GABRP | O00591 | 2/20 | 0.51 |
| ▸ | GABRD | O14764 | 2/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.51 |
| ▸ | GABRE | P78334 | 2/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13524249 | 0.78 | GABRA1 (0.40) | GABRA1GABRA5GABRA2GABRA3GABRG2 | |
| SCHEMBL29588960 | 0.75 | GABRA1 (1.00) | GABRA1GABRA5GABRA2GABRA3GABRG2 | |
| SCHEMBL2871536 | 0.75 | GABRA1 (1.00) | GABRA1GABRA5GABRA2GABRA3GABRG2 | |
| SCHEMBL7724649 | 0.74 | GABRA1 (0.36) | GABRA1GABRA5GABRA2GABRA3GABRG2 | |
| SCHEMBL14217768 | 0.71 | GABRG2 (0.45) | GABRA1GABRA5GABRA2GABRA3GABRG2 | |
| SCHEMBL13009565 | 0.71 | CCKBR (0.38) | GABRA1GABRA5GABRA2GABRA3GABRG2 | |
| SCHEMBL877728 | 0.71 | GABRA1 (1.00) | GABRA1GABRA5GABRA2GABRA3GABRG2 | |
| SCHEMBL30175096 | 0.71 | GABRA1 (1.00) | GABRA1GABRA5GABRA2GABRA3GABRG2 | |
| SCHEMBL8363061 | 0.69 | GABRG2 (0.47) | GABRA1GABRA5GABRA2GABRA3GABRG2 | |
| SCHEMBL14217646 | 0.69 | GABRA1 (0.34) | GABRA1GABRA5GABRA2GABRA3GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE47475-E1 | Selective agents for pain suppression | WISYS TECHNOLOGY FOUNDATION, INC. (US) | 2019-07-02 | — | — | US | disclosed |
| US-8835424-B2 | Selective agents for pain suppression | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-09-16 | — | — | US | disclosed |
| EP-1925614-A1 | Anxiolytic agents with reduced sedative and ataxic effects | Wisys Technology Foundation, Inc. (US) | 2008-05-28 | — | — | EP | disclosed |