Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 12/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTAFR | P25105 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19922696 | 0.85 | GABRA3 (0.54) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL8349557 | 0.84 | GABRA3 (0.47) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL13061778 | 0.84 | GABRA3 (0.70) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL637130 | 0.83 | GABRG2 (0.56) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL19929180 | 0.82 | GABRA3 (0.51) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL19368412 | 0.82 | GABRA3 (0.56) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL2845958 | 0.82 | GABRG2 (0.77) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL19929209 | 0.81 | GABRA3 (0.58) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL18096716 | 0.79 | GABRA3 (0.76) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL11509201 | 0.79 | GABRA1 (0.49) | GABRG2GABRB3GABRA3GABRA5GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1925614-A1 | Anxiolytic agents with reduced sedative and ataxic effects | Wisys Technology Foundation, Inc. (US) | 2008-05-28 | — | — | EP | disclosed |