Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.37 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14217850 | 0.85 | MAPK1 (0.49) | L3MBTL1MAPK1MAPTNPSR1ALDH1A1 | |
| SCHEMBL14217849 | 0.81 | MAPK1 (0.45) | L3MBTL1MAPK1MAPTNPSR1ALDH1A1 | |
| SCHEMBL14190585 | 0.77 | ALDH1A1 (0.36) | L3MBTL1MAPK1NPSR1ALDH1A1SLC15A1 | |
| SCHEMBL7306613 | 0.73 | ALDH1A1 (0.45) | L3MBTL1MAPK1NPSR1ALDH1A1TDP1 | |
| SCHEMBL7306627 | 0.73 | ALDH1A1 (0.45) | L3MBTL1MAPK1NPSR1ALDH1A1SLC15A1 | |
| SCHEMBL15776096 | 0.72 | ALDH1A1 (0.61) | L3MBTL1MAPK1NPSR1ALDH1A1TSHR | |
| SCHEMBL1880257 | 0.71 | ALDH1A1 (0.56) | L3MBTL1MAPK1ALDH1A1TSHRTDP1 | |
| SCHEMBL8930189 | 0.71 | ALDH1A1 (0.66) | L3MBTL1MAPK1MAPTALDH1A1TSHR | |
| SCHEMBL6032352 | 0.71 | ALDH1A1 (0.66) | L3MBTL1MAPK1MAPTALDH1A1TSHR | |
| SCHEMBL13259771 | 0.71 | ALDH1A1 (0.66) | L3MBTL1MAPK1MAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080124270-A1 | Compounds Useful as Metal Chelators | BRACCO IMAGING S.P.A. (IT) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080124270-A1 | Compounds Useful as Metal Chelators | PAICS, PHOSPHO1, PPIP5K2 | L3MBTL1 2920/4885MAPK1 3967/4885MAPT 4159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.