Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306627 | 0.84 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPK1SLC15A1KMT2A | |
| SCHEMBL9044314 | 0.76 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAPK1KMT2ANOTUM | |
| SCHEMBL19420152 | 0.75 | POLB (0.59) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL11114975 | 0.74 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1MAPK1KMT2ANOTUM | |
| SCHEMBL20538365 | 0.73 | RAB9A (0.46) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL17629527 | 0.73 | RAB9A (0.46) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL14217850 | 0.73 | MAPK1 (0.49) | ALDH1A1L3MBTL1MAPK1SLC15A1NPSR1 | |
| SCHEMBL14217848 | 0.73 | L3MBTL1 (0.49) | ALDH1A1L3MBTL1MAPK1SLC15A1KMT2A | |
| SCHEMBL42127 | 0.73 | MEN1 (0.66) | L3MBTL1KMT2AMEN1NPSR1CYP2C9 | |
| SCHEMBL7306734 | 0.73 | MAPT (0.47) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | claimed |
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |