Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.56 |
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 5/20 | 0.51 |
| ▸ | TPSG1 | Q9NRR2 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22224323 | 0.98 | EPHX1 (0.59) | EPHX1TPSAB1TPSD1TPSG1GAA | |
| SCHEMBL22895264 | 0.88 | TPSAB1 (0.45) | EPHX1TPSAB1TPSD1TPSG1GAA | |
| SCHEMBL19692284 | 0.88 | TPSAB1 (0.45) | EPHX1TPSAB1TPSD1TPSG1GAA | |
| SCHEMBL19692282 | 0.88 | TPSAB1 (0.45) | EPHX1TPSAB1TPSD1TPSG1GAA | |
| SCHEMBL17402089 | 0.88 | TPSAB1 (0.45) | EPHX1TPSAB1TPSD1TPSG1GAA | |
| Hydrochloric Acid SCHEMBL30689874 | 0.86 | TPSAB1 (0.44) | EPHX1TPSAB1TPSD1TPSG1GAA | |
| SCHEMBL10879403 | 0.85 | EPHX1 (0.65) | EPHX1TPSAB1TPSD1TPSG1GAA | |
| SCHEMBL10817282 | 0.83 | EPHX1 (0.71) | EPHX1GAAHDAC3HDAC1HDAC2 | |
| SCHEMBL22134964 | 0.82 | EPHX1 (0.66) | EPHX1GAANAAABCHE | |
| SCHEMBL8430616 | 0.82 | EPHX1 (0.56) | EPHX1TPSAB1TPSD1TPSG1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080107680-A1 | Modified Human Growth Hormone | AMBRX, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080107680-A1 | Modified Human Growth Hormone | GHRHR, GHITM, GHSR | EPHX1 4442/4885TPSAB1 3129/4885TPSD1 3441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.