Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | HRH1 | P35367 | 8/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13478801 | 0.98 | HTR6 (0.55) | HTR6CA1CA2HRH1CNR2 | |
| SCHEMBL14218042 | 0.83 | HRH1 (0.60) | HTR6CA1CA2HRH1CNR2 | |
| SCHEMBL14218080 | 0.81 | EGFR (0.42) | HTR6HRH1CNR2 | |
| SCHEMBL14218046 | 0.81 | HTR6 (0.47) | HTR6CA1CA2HRH1 | |
| SCHEMBL13563257 | 0.81 | HTR6 (0.46) | HTR6CA1CA2USP2 | |
| SCHEMBL13478810 | 0.81 | HTR6 (0.60) | HTR6CA1CA2HRH1CNR2 | |
| SCHEMBL13478813 | 0.79 | HTR6 (0.50) | HTR6CA1CA2 | |
| SCHEMBL13563240 | 0.78 | HTR6 (0.53) | HTR6CA1CA2HRH1 | |
| SCHEMBL13563338 | 0.77 | HTR6 (0.53) | HTR6CA1CA2 | |
| SCHEMBL14624291 | 0.77 | HTR6 (0.59) | HTR6CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063867-A2 | TETRAHYDROCYCLOPENTA[B] INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2008-05-29 | — | — | WO | disclosed |