Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13478813 | 0.98 | HTR6 (0.50) | HTR6CA1CA2PTGS1PTGS2 | |
| SCHEMBL14217953 | 0.84 | SCARB1 (0.49) | HTR6CA1CA2PTGS1PTGS2 | |
| SCHEMBL14217957 | 0.81 | HTR6 (0.52) | HTR6CA1CA2HRH1 | |
| SCHEMBL14218045 | 0.81 | SIGMAR1 (0.35) | HTR6PTGDR2PARGHRH1 | |
| SCHEMBL13478801 | 0.79 | HTR6 (0.55) | HTR6CA1CA2PTGS1PTGS2 | |
| SCHEMBL13478762 | 0.77 | HTR6 (0.58) | HTR6CA1CA2PTGS1PTGS2 | |
| SCHEMBL14623681 | 0.77 | PTGDR2 (0.42) | PTGDR2 | |
| SCHEMBL13563336 | 0.76 | HTR6 (0.46) | HTR6CA1CA2PTGS1PTGS2 | |
| SCHEMBL14624590 | 0.76 | PTGDR2 (0.42) | HTR6PTGDR2 | |
| SCHEMBL13478782 | 0.74 | HTR6 (0.51) | HTR6CA1CA2PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063867-A2 | TETRAHYDROCYCLOPENTA[B] INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2008-05-29 | — | — | WO | disclosed |