Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 2/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14217936 | 0.88 | DRD2 (0.33) | PTGDR2PARGBCHEACHE | |
| SCHEMBL14217935 | 0.88 | DRD2 (0.33) | PTGDR2PARGBCHEACHE | |
| SCHEMBL12578994 | 0.87 | PTGDR2 (0.35) | PTGDR2MTNR1AMTNR1BPARGF10 | |
| SCHEMBL2027519 | 0.87 | PTGDR2 (0.35) | PTGDR2MTNR1AMTNR1BPARGF10 | |
| SCHEMBL2028675 | 0.87 | PTGDR2 (0.35) | PTGDR2MTNR1AMTNR1BPARGF10 | |
| SCHEMBL14217938 | 0.86 | ELANE (0.34) | PTGDR2PARGPLA2G2ABCHEACHE | |
| SCHEMBL16493855 | 0.85 | S1PR3 (0.40) | PTGDR2MTNR1AMTNR1BPARGBCHE | |
| SCHEMBL16493857 | 0.85 | S1PR3 (0.40) | PTGDR2MTNR1AMTNR1BPARGBCHE | |
| SCHEMBL14624590 | 0.81 | PTGDR2 (0.42) | PTGDR2BCHEACHE | |
| SCHEMBL1875556 | 0.81 | PTGDR2 (0.42) | PTGDR2MTNR1AMTNR1BF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063867-A2 | TETRAHYDROCYCLOPENTA[B] INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2008-05-29 | — | — | WO | disclosed |