Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | PARG | Q86W56 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14217936 | 1.00 | DRD2 (0.33) | DRD2PTGDR2HTR1AHTR2APARG | |
| SCHEMBL14217938 | 0.91 | ELANE (0.34) | PTGDR2PARGBCHEACHE | |
| SCHEMBL2025967 | 0.88 | PTGDR2 (0.33) | DRD2PTGDR2HTR1AHTR2APARG | |
| SCHEMBL2025356 | 0.88 | PTGDR2 (0.33) | DRD2PTGDR2HTR1AHTR2APARG | |
| SCHEMBL12579044 | 0.88 | PTGDR2 (0.33) | DRD2PTGDR2HTR1AHTR2APARG | |
| SCHEMBL2026354 | 0.88 | PTGDR2 (0.33) | DRD2PTGDR2HTR1AHTR2APARG | |
| SCHEMBL14217996 | 0.88 | PTGDR2 (0.34) | PTGDR2PARGBCHEACHE | |
| SCHEMBL14218054 | 0.87 | PLA2G2A (0.38) | DRD2 | |
| SCHEMBL14218051 | 0.87 | PLA2G2A (0.38) | DRD2 | |
| SCHEMBL14624590 | 0.83 | PTGDR2 (0.42) | PTGDR2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063867-A2 | TETRAHYDROCYCLOPENTA[B] INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2008-05-29 | — | — | WO | disclosed |