Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4376244 | 0.85 | NPC1 (0.59) | ALDH1A1HPGDMAPTPOLBKMT2A | |
| SCHEMBL4378626 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTPOLBKMT2A | |
| SCHEMBL4379550 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HPGDMAPTPOLBKDM4E | |
| SCHEMBL4375723 | 0.80 | TSHR (0.52) | ALDH1A1HPGDMAPTPOLBKMT2A | |
| SCHEMBL2852216 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HPGDMAPTPOLBKMT2A | |
| SCHEMBL14218057 | 0.74 | KMT2A (0.55) | ALDH1A1HPGDMAPTPOLBKMT2A | |
| SCHEMBL3070296 | 0.73 | POLB (0.62) | ALDH1A1HPGDMAPTPOLBKMT2A | |
| SCHEMBL14218059 | 0.73 | KMT2A (0.67) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL3047400 | 0.68 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTPOLBKMT2A | |
| SCHEMBL2377627 | 0.68 | KMT2A (0.77) | ALDH1A1HPGDKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113968-A1 | Substituted piperazines and diazepanes | NOVO NORDISK A/S (DK) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113968-A1 | Substituted piperazines and diazepanes | HRH3, HRH4, HRH1 | ALDH1A1 1907/4885HPGD 646/4885MAPT 1441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.