SCHEMBL14218129

SCHEMBL14218129

CC(C)(C)OC(=O)N1CCC(COc2ccc(-c3ccc(CN)cc3)nc2)CC1

nearest known ligand 0.70

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 9/20 0.70
HDAC1 Q13547 1/20 0.54
CHEK2 O96017 1/20 0.51
CYP4F2 P78329 6/20 0.51
CYP4A11 Q02928 6/20 0.51
ALOX5AP P20292 1/20 0.49
FEN1 P39748 1/20 0.49
SLC2A1 P11166 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3982603 0.90 GPR119 (0.69) GPR119HDAC1CHEK2CYP4F2CYP4A11
SCHEMBL14191030 0.88 GPR119 (0.67) GPR119HDAC1CHEK2CYP4F2CYP4A11
SCHEMBL15538390 0.87 GPR119 (0.77) GPR119HDAC1CHEK2CYP4F2CYP4A11
SCHEMBL3982355 0.87 GPR119 (0.77) GPR119HDAC1CHEK2CYP4F2CYP4A11
SCHEMBL14191024 0.87 GPR119 (0.66) GPR119HDAC1CHEK2CYP4F2CYP4A11
SCHEMBL14191034 0.86 GPR119 (0.65) GPR119HDAC1CHEK2CYP4F2CYP4A11
SCHEMBL387392 0.86 GPR119 (0.69) GPR119
SCHEMBL14191036 0.86 GPR119 (0.64) GPR119HDAC1CHEK2CYP4F2CYP4A11
SCHEMBL14191020 0.85 GPR119 (0.68) GPR119HDAC1CHEK2CYP4F2CYP4A11
SCHEMBL14191032 0.85 GPR119 (0.68) GPR119HDAC1CHEK2CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080103123-A1 New compounds BIOVITRUM (SE) 2008-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080103123-A1 New compounds GPR119, GPR139, GPR180 GPR119 1/4885HDAC1 2847/4885CHEK2 4217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.