SCHEMBL14218149

SCHEMBL14218149

CCCNCC(N)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ANPEP P15144 3/20 0.52
▸ GRIK1 P39086 6/20 0.44
▸ SLC1A2 P43004 5/20 0.44
▸ SLC1A1 P43005 5/20 0.44
▸ GRIK2 Q13002 5/20 0.44
▸ SLC1A3 P43003 4/20 0.44
▸ SLC7A5 Q01650 1/20 0.41
▸ ERAP2 Q6P179 2/20 0.41
▸ GFPT1 Q06210 1/20 0.41
▸ PTGS1 P23219 1/20 0.39
▸ SLC7A11 Q9UPY5 1/20 0.39
▸ GRIA4 P48058 1/20 0.38
▸ GRIK3 Q13003 1/20 0.38
▸ GRIK5 Q16478 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14674293 0.86 ANPEP (0.54) ANPEPGRIK1SLC1A2SLC1A1GRIK2
SCHEMBL10676946 0.82 — —
SCHEMBL17434128 0.81 PTGS1 (0.50) GRIK1SLC1A2SLC1A1GRIK2SLC1A3
SCHEMBL19368124 0.81 SLC1A2 (0.47) ANPEPGRIK1SLC1A2SLC1A1GRIK2
SCHEMBL29951736 0.80 PTGS1 (0.41) GRIK1SLC1A2SLC1A1GRIK2SLC1A3
SCHEMBL8892460 0.80 GSR (0.48) GRIK1SLC1A2SLC1A1GRIK2SLC1A3
SCHEMBL28766764 0.80 PTGS1 (0.41) GRIK1SLC1A2SLC1A1GRIK2SLC1A3
SCHEMBL7270272 0.80 GSR (0.50) ANPEPGRIK1SLC1A2SLC1A1GRIK2
SCHEMBL5576905 0.80 GSR (0.50) ANPEPGRIK1SLC1A2SLC1A1GRIK2
SCHEMBL12643504 0.80 GSR (0.50) ANPEPGRIK1SLC1A2SLC1A1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160346402-A1 ANTIBODY DRUG CONJUGATES (ADCS) WITH KINESIN SPINDEL PROTEIN (KSP) BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-12-01 — — US disclosed
US-7378386-B2 Anti-viral treatment methods using phosphatidylethanolamine-binding peptide derivatives BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2008-05-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160346402-A1 ANTIBODY DRUG CONJUGATES (ADCS) WITH KINESIN SPINDEL PROTEIN (KSP) KIF5B, KIF23, KIF2C ANPEP 3547/4885GRIK1 874/4885SLC1A2 1606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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