SCHEMBL14218182

SCHEMBL14218182

CCNC(=O)N(C)CCCN(C)C

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 4/20 0.41
EPHX2 P34913 2/20 0.38
ALDH1A1 P00352 2/20 0.36
GAA P10253 1/20 0.36
PAOX Q6QHF9 1/20 0.35
TSHR P16473 1/20 0.35
KDM4A O75164 5/20 0.34
KDM4C Q9H3R0 5/20 0.34
KDM5A P29375 1/20 0.34
KDM7A Q6ZMT4 1/20 0.34
PHF8 Q9UPP1 1/20 0.34
KDM2A Q9Y2K7 1/20 0.34
KDM4E B2RXH2 2/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL968056 0.85 EPHX2 (0.45) DNM1EPHX2ALDH1A1GAAKDM4A
SCHEMBL12315677 0.83 DNM1 (0.41) DNM1ALDH1A1GAAPAOXTSHR
SCHEMBL23139649 0.82 EPHX2 (0.54) DNM1EPHX2KDM4CKDM5APHF8
SCHEMBL3237502 0.82 EPHX2 (0.37) DNM1EPHX2ALDH1A1GAAPAOX
SCHEMBL969640 0.80 ALDH1A1 (0.39) DNM1EPHX2ALDH1A1GAATSHR
SCHEMBL26942480 0.80 DNM1 (0.39) DNM1ALDH1A1GAAPAOXKDM4A
SCHEMBL1922660 0.80 DNM1 (0.39) DNM1ALDH1A1GAAPAOXTSHR
SCHEMBL15727671 0.79 DNM1 (0.38) DNM1ALDH1A1GAAPAOXKDM4A
SCHEMBL10090412 0.78 MAPT (0.39) DNM1EPHX2ALDH1A1GAA
SCHEMBL3265186 0.78 ROCK2 (0.39) DNM1ALDH1A1PAOXTSHRKDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023239719-A1 CHEMICALLY MODIFIED HEPARIN IHP THERAPEUTICS INC. (US) 2023-12-14 WO disclosed
WO-2023239711-A1 CHEMICALLY MODIFIED HEPARIN IHP THERAPEUTICS INC. (US) 2023-12-14 WO disclosed
US-7371877-B2 Glycerol ester derivative FUJIFILM CORPORATION (JP) 2008-05-13 US disclosed