SCHEMBL1421889

SCHEMBL1421889

COCC(=O)c1ccc(OC)c(OC)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.73
TSHR P16473 2/20 0.73
CYP1A2 P05177 1/20 0.63
CYP3A4 P08684 1/20 0.63
CYP2C9 P11712 1/20 0.63
CYP2C19 P33261 1/20 0.63
CTNNB1 P35222 2/20 0.63
WNT3A P56704 2/20 0.63
ALDH1A1 P00352 3/20 0.62
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CA4 P22748 1/20 0.61
CA6 P23280 1/20 0.61
CA7 P43166 1/20 0.61
TPMT P51580 1/20 0.61
CA9 Q16790 1/20 0.61
CA14 Q9ULX7 1/20 0.61
ACHE P22303 2/20 0.58
MEN1 O00255 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9417798 0.86 MAPT (0.55) MAPTTSHRCYP1A2CYP3A4CYP2C9
SCHEMBL11335265 0.86 MAPT (0.55) MAPTTSHRCYP1A2CYP3A4CYP2C9
SCHEMBL16360980 0.86 MEN1 (0.66) MAPTTSHRCYP1A2ALDH1A1MEN1
SCHEMBL10455919 0.85 CTNNB1 (0.83) MAPTTSHRCYP1A2CYP3A4CYP2C9
SCHEMBL1659363 0.85 MAPT (0.71) MAPTTSHRCYP1A2CYP3A4CYP2C9
SCHEMBL9027956 0.84 TSHR (0.77) MAPTTSHRCYP1A2CYP3A4CYP2C9
SCHEMBL28957149 0.84 ALDH1A1 (0.67) MAPTTSHRCYP1A2CYP3A4CYP2C9
SCHEMBL1219390 0.84 MAPT (0.54) MAPTTSHRCYP1A2CYP3A4CYP2C9
SCHEMBL28852550 0.84 MAPT (0.54) MAPTTSHRCYP1A2CYP3A4CYP2C9
SCHEMBL515746 0.83 MEN1 (0.73) MAPTTSHRCYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US claimed
US-20240392094-A1 Method for Screening Solvent for Polyvinyl Chloride Extraction, Recycling Method for Waste Material, and Recycled Polyvinyl Chloride and Composition LG CHEM, LTD. (KR) 2024-11-28 US claimed
WO-2023033605-A1 METHOD FOR SCREENING SOLVENT FOR EXTRACTING POLYVINYL CHLORIDE, METHOD FOR RECYCLING WASTE, RECYCLED POLYVINYL CHLORIDE, AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO claimed
WO-2023033601-A1 METHOD FOR SCREENING SOLVENT FOR POLYVINYL CHLORIDE EXTRACTION, RECYCLING METHOD FOR WASTE MATERIAL, AND RECYCLED POLYVINYL CHLORIDE AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO claimed
US-20250170111-A1 PYRIDINE BASED CHALCONE ANALOGS AS THERAPEUTIC AGENTS AND USE THEREOF QATAR UNIVERSITY (QA) 2025-05-29 US disclosed
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US disclosed
US-20240392094-A1 Method for Screening Solvent for Polyvinyl Chloride Extraction, Recycling Method for Waste Material, and Recycled Polyvinyl Chloride and Composition LG CHEM, LTD. (KR) 2024-11-28 US disclosed
CN-114890947-B Aromatic heterocyclic compound containing quinoline structural unit, and preparation method and application thereof 郑州大学 2024-07-16 CN disclosed
CN-117897440-A Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN disclosed
WO-2023033605-A1 METHOD FOR SCREENING SOLVENT FOR EXTRACTING POLYVINYL CHLORIDE, METHOD FOR RECYCLING WASTE, RECYCLED POLYVINYL CHLORIDE, AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO disclosed
WO-2023033601-A1 METHOD FOR SCREENING SOLVENT FOR POLYVINYL CHLORIDE EXTRACTION, RECYCLING METHOD FOR WASTE MATERIAL, AND RECYCLED POLYVINYL CHLORIDE AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO disclosed
CN-114890947-A Aromatic heterocyclic compound containing quinoline structural unit and preparation method and application thereof 郑州大学 2022-08-12 CN disclosed
US-5446146-A Treatment of liver disorders NIPPON CHEMIPHAR CO., LTD. (JP) 1995-08-29 US disclosed
US-5428037-A Piperazine derivatives; calcium and sodium channel antagonists SYNTEX PHARMACEUTICALS, LTD. (GB) 1995-06-27 US disclosed
EP-0326379-B1 Therapeutic agent for liver disease and piperazine derivatives NIPPON CHEMIPHAR CO (JP) 1994-06-01 EP disclosed
US-5070089-A INHIBITION OF LIPID PEROXIDATION NIPPON CHEMIPHAR CO., LTD. (JP) 1991-12-03 US disclosed
EP-0328669-A1 CHALCONE DERIVATIVE COMPOUNDS NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-08-23 EP disclosed
EP-0326379-A2 Therapeutic agent for liver disease and piperazine derivatives NIPPON CHEMIPHAR CO., LTD. (JP) 1989-08-02 EP disclosed
US-4450292-A ANTISECRETORY AND ANTIULCER AGENTS; ROUSSEL UCLAF (FR) 1984-05-22 US disclosed
US-4436752-A ANTISECRETORY, ANTIULCER ROUSSEL UCLAF (FR) 1984-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250170111-A1 PYRIDINE BASED CHALCONE ANALOGS AS THERAPEUTIC AGENTS AND USE THEREOF HCCS, PDXK, NOD1 MAPT 1511/4885TSHR 3769/4885CYP1A2 1133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.