Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21558455 | 0.82 | KDM4E (0.54) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL8173931 | 0.80 | NQO1 (0.46) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL15172350 | 0.80 | L3MBTL1 (0.47) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL14609038 | 0.79 | CYP19A1 (0.47) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL4044027 | 0.79 | HPGD (0.64) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL16957387 | 0.79 | TSHR (0.64) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL16950428 | 0.79 | L3MBTL1 (0.45) | MAPTMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL8906528 | 0.77 | CYP1A1 (0.45) | MAPTKDM4EGAAKMT2AHTT | |
| SCHEMBL21571920 | 0.77 | ALDH1A1 (0.40) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL31095359 | 0.77 | MAPT (0.78) | MAPTKDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008047883-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-04-24 | — | — | WO | disclosed |