Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18556285 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1CYP2D6THRA | |
| SCHEMBL12775614 | 0.80 | CALM1 (0.46) | ALDH1A1KMT2AMEN1CYP2D6TSHR | |
| SCHEMBL14218923 | 0.77 | MAPT (0.54) | ALDH1A1KMT2AMEN1THRBTSHR | |
| SCHEMBL12775648 | 0.76 | CALM1 (0.50) | ALDH1A1KMT2AMAPTKDM4EGAA | |
| SCHEMBL12775657 | 0.76 | CALM1 (0.58) | ALDH1A1KMT2ATSHRLMNAMAPT | |
| SCHEMBL15177279 | 0.76 | KDM1A (0.45) | ALDH1A1MAPTKDM4EGAAESR1 | |
| SCHEMBL8173931 | 0.75 | NQO1 (0.46) | ALDH1A1KMT2AMEN1CYP2D6TSHR | |
| SCHEMBL15172350 | 0.75 | L3MBTL1 (0.47) | ALDH1A1KMT2AMEN1TSHRHPGD | |
| SCHEMBL4044027 | 0.73 | HPGD (0.64) | ALDH1A1KMT2AMEN1CYP2D6TSHR | |
| SCHEMBL16957387 | 0.73 | TSHR (0.64) | ALDH1A1KMT2AMEN1CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10479861-B2 | Catalytic carbonylation catalysts and methods | NOVOMER, INC. (US) | 2019-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10479861-B2 | Catalytic carbonylation catalysts and methods | CBR3, CBR1, EPHX2 | ALDH1A1 181/4885KMT2A 954/4885MEN1 2827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.