Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14218962 | 0.94 | THRB (0.41) | THRBSCN1ASCN2ASCN3ATHRA | |
| SCHEMBL14218972 | 0.91 | SCN1A (0.39) | THRBSCN1ASCN2ASCN3ATHRA | |
| SCHEMBL565179 | 0.71 | TSHR (0.46) | THRBTHRAALDH1A1LMNA | |
| SCHEMBL14192523 | 0.71 | SCN1A (0.44) | THRBSCN1ASCN2ASCN3ATHRA | |
| SCHEMBL14218976 | 0.70 | THRB (0.42) | THRBTHRAALDH1A1MEN1KMT2A | |
| SCHEMBL20615579 | 0.69 | THRB (0.47) | THRBSCN1ASCN2ASCN3AHTT | |
| SCHEMBL13296235 | 0.69 | CCR2 (0.31) | — | |
| SCHEMBL1356970 | 0.68 | TSHR (0.32) | — | |
| SCHEMBL14219065 | 0.67 | THRB (0.40) | THRBTHRAALDH1A1MEN1KMT2A | |
| SCHEMBL28298605 | 0.67 | TSHR (0.44) | THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |