SCHEMBL14219409

SCHEMBL14219409

CCCc1ccc(-c2c(F)cc(C3CCC(C[C@H](C)c4ccccc4)CC3)cc2F)cc1F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.31
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14219475 0.90 DGAT1 (0.33) IDO1APP
SCHEMBL14219412 0.90 DGAT1 (0.33) IDO1APP
SCHEMBL14220037 0.88 IDO1 (0.32) IDO1
SCHEMBL14220030 0.86 RORC (0.33) IDO1
SCHEMBL14219322 0.86 RORC (0.33) IDO1
SCHEMBL14219595 0.86 RORC (0.33) IDO1
SCHEMBL14219331 0.86 RORC (0.33) IDO1
SCHEMBL14220034 0.84 CYP17A1 (0.35) IDO1APP
SCHEMBL14220000 0.82 SPHK1 (0.34) IDO1
SCHEMBL14219484 0.82 SPHK1 (0.34) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1650285-B1 Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element SEIMI CHEM KK (JP) 2008-04-30 EP disclosed