Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 13/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | INSR | P06213 | 1/20 | 0.31 |
| ▸ | PTGIR | P43119 | 1/20 | 0.31 |
| ▸ | CASP9 | P55211 | 1/20 | 0.31 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219412 | 1.00 | DGAT1 (0.33) | DGAT1APPIDO1NPC1RAB9A | |
| SCHEMBL14219409 | 0.90 | IDO1 (0.31) | APPIDO1 | |
| SCHEMBL14219484 | 0.88 | SPHK1 (0.34) | IDO1 | |
| SCHEMBL14220000 | 0.88 | SPHK1 (0.34) | IDO1 | |
| SCHEMBL14219422 | 0.88 | DGAT1 (0.34) | DGAT1APPIDO1NPC1RAB9A | |
| SCHEMBL14219326 | 0.88 | DGAT1 (0.34) | DGAT1APPIDO1NPC1RAB9A | |
| SCHEMBL14219595 | 0.88 | RORC (0.33) | IDO1 | |
| SCHEMBL14220030 | 0.88 | RORC (0.33) | IDO1CTSK | |
| SCHEMBL14219322 | 0.88 | RORC (0.33) | IDO1CTSK | |
| SCHEMBL14219331 | 0.88 | RORC (0.33) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650285-B1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEM KK (JP) | 2008-04-30 | — | — | EP | disclosed |