SCHEMBL1421942

SCHEMBL1421942

NCCCCCC(=O)C([C]=O)CCCCN

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
PLG P00747 1/20 0.43
LMNA P02545 1/20 0.43
THRB P10828 1/20 0.43
ALOX15 P16050 1/20 0.43
SLC6A2 P23975 1/20 0.43
RECQL P46063 1/20 0.43
SLC6A3 Q01959 1/20 0.43
KMT2A Q03164 1/20 0.43
PAOX Q6QHF9 2/20 0.42
CYP2D6 P10635 1/20 0.40
NFKB1 P19838 1/20 0.40
GSR P00390 1/20 0.39
CPB2 Q96IY4 5/20 0.39
BLM P54132 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RNPEP Q9H4A4 1/20 0.38
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7293344 1.00 MEN1 (0.43) MEN1ALDH1A1PLGLMNATHRB
SCHEMBL7159116 1.00 MEN1 (0.43) MEN1ALDH1A1PLGLMNATHRB
SCHEMBL934384 0.92 CES2 (0.44) MEN1KMT2ASLC6A5GNAI3GNAO1
SCHEMBL2770560 0.86 GNAI3 (0.42) MEN1KMT2AGNAI3GNAO1GNAI1
SCHEMBL9119248 0.81 CES2 (0.52)
SCHEMBL4958852 0.81 CES2 (0.52)
SCHEMBL8917791 0.81 CES2 (0.52)
SCHEMBL2304845 0.81 CES2 (0.52)
SCHEMBL5802863 0.81 CES2 (0.52)
SCHEMBL9868874 0.81 CES2 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110191867-A1 PEPTIDE VACCINE FOR INFLUENZA VIRUS GLYKOS FINLAND OY (FI) 2011-08-04 US disclosed
EP-2296688-A2 PEPTIDE VACCINE FOR INFLUENZA VIRUS Glykos Finland Oy (FI) 2011-03-23 EP disclosed
US-20100081629-A1 LOW MOLECULAR WEIGHT HEPARINS INCLUDING AT LEAST ONE COVALENT BOND WITH BIOTIN OR A BIOTIN DERIVATIVE, METHOD FOR MAKING SAME AND USE THEREOF SANOFI-AVENTIS (FR) 2010-04-01 US disclosed
US-20100074920-A1 PEPTIDE VACCINE FOR INFLUENZA VIRUS GLYKOS FINLAND OY (FI) 2010-03-25 US disclosed
EP-2121769-A1 LOW MOLECULAR WEIGHT HEPARINS INCLUDING AT LEAST ONE COVALENT BOND WITH BIOTIN OR A BIOTIN DERIVATIVE, METHOD FOR MAKING SAME AND USE THEREOF Sanofi-Aventis (FR) 2009-11-25 EP disclosed
WO-2009133249-A1 PEPTIDE VACCINE FOR INFLUENZA VIRUS GLYKOS FINLAND OY (FI) 2009-11-05 WO disclosed
EP-2091960-A2 PEPTIDE VACCINE FOR INFLUENZA VIRUS Glykos Finland Oy (FI) 2009-08-26 EP disclosed
WO-2009053535-A2 PEPTIDE VACCINE FOR INFLUENZA VIRUS GLYKOS FINLAND OY (FI) 2009-04-30 WO disclosed
WO-2008113919-A1 LOW MOLECULAR WEIGHT HEPARINS INCLUDING AT LEAST ONE COVALENT BOND WITH BIOTIN OR A BIOTIN DERIVATIVE, METHOD FOR MAKING SAME AND USE THEREOF SANOFI-AVENTIS (FR) 2008-09-25 WO disclosed
WO-2008049974-A2 PEPTIDE VACCINE FOR INFLUENZA VIRUS GLYKOS FINLAND OY (FI) 2008-05-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100074920-A1 PEPTIDE VACCINE FOR INFLUENZA VIRUS SIGLEC7, SIGLEC9, NEU3 MEN1 2385/4885ALDH1A1 4602/4885PLG 3788/4885
US-20100081629-A1 LOW MOLECULAR WEIGHT HEPARINS INCLUDING AT LEAST ONE COVALENT BOND WITH BIOTIN OR A BIOTIN DERIVATIVE, METHOD FOR MAKING SAME AND USE THEREOF BTD, CD44, HLCS MEN1 2181/4885ALDH1A1 1755/4885PLG 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.