Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 15/20 | 0.33 |
| ▸ | S100A9 | P06702 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14220144 | 0.90 | HTT (0.38) | DHODHHTTIRAK4 | |
| SCHEMBL14220138 | 0.89 | HTT (0.37) | DHODHHTTIRAK4 | |
| SCHEMBL14219820 | 0.85 | DHODH (0.40) | DHODH | |
| SCHEMBL14222457 | 0.83 | DHODH (0.41) | DHODH | |
| SCHEMBL14219735 | 0.80 | MAP2K1 (0.48) | IRAK4 | |
| SCHEMBL14219625 | 0.80 | MAP2K1 (0.48) | IRAK4 | |
| SCHEMBL14223199 | 0.76 | DHODH (0.51) | DHODHHTTIRAK4 | |
| SCHEMBL14219689 | 0.76 | DHODH (0.39) | DHODH | |
| SCHEMBL14219691 | 0.75 | DHODH (0.44) | DHODHIRAK4 | |
| SCHEMBL14219822 | 0.73 | DHODH (0.38) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |