Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 4/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 12/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14220138 | 0.92 | HTT (0.37) | HTTDHODHIRAK4MAP2K1 | |
| SCHEMBL14219609 | 0.90 | DHODH (0.37) | HTTDHODHIRAK4 | |
| SCHEMBL14219822 | 0.84 | DHODH (0.38) | DHODHMAP2K1 | |
| SCHEMBL14219814 | 0.81 | DHODH (0.43) | DHODHMAP2K1 | |
| SCHEMBL14219846 | 0.78 | MAP2K1 (0.56) | IRAK4MAP2K1 | |
| SCHEMBL14219677 | 0.78 | DHODH (0.39) | DHODHIRAK4MAP2K1 | |
| SCHEMBL14220139 | 0.76 | NPC1 (0.38) | DHODHMAP2K1 | |
| SCHEMBL14219688 | 0.74 | LMNA (0.36) | DHODHMAP2K1 | |
| SCHEMBL14220106 | 0.74 | DHODH (0.46) | DHODHMAP2K1 | |
| SCHEMBL14219820 | 0.73 | DHODH (0.40) | DHODHMAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |