Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.33 |
| ▸ | SMC2 | O95347 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SMC1A | Q14683 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.33 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.30 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14220130 | 0.90 | ALDH1A1 (0.37) | ALDH1A1MAP2K1CSNK2A2MAP2K2SMC2 | |
| SCHEMBL14220157 | 0.90 | MEN1 (0.42) | ALDH1A1MAP2K1MAP2K2MEN1KMT2A | |
| SCHEMBL14219727 | 0.88 | MEN1 (0.34) | MAP2K1CSNK2A2MAP2K2SMC2EGFR | |
| SCHEMBL14219716 | 0.87 | ALDH1A1 (0.36) | ALDH1A1MAP2K1CSNK2A2MAP2K2SMC2 | |
| SCHEMBL14220164 | 0.86 | PTGS2 (0.36) | MAP2K1CSNK2A2MAP2K2SMC2EGFR | |
| SCHEMBL14219659 | 0.84 | MAP2K1 (0.44) | MAP2K1CSNK2A2MAP2K2SMC2EGFR | |
| SCHEMBL14223049 | 0.83 | MAP2K1 (0.37) | ALDH1A1MAP2K1CSNK2A2MAP2K2SMC2 | |
| SCHEMBL14219743 | 0.83 | MEN1 (0.42) | ALDH1A1MAP2K1CSNK2A2MAP2K2SMC2 | |
| SCHEMBL14223224 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL14222456 | 0.81 | DHODH (0.39) | MAP2K1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |