Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.34 |
| ▸ | SMC2 | O95347 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SMC1A | Q14683 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.34 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | TXK | P42681 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219657 | 0.90 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ATDP1MAP2K1 | |
| SCHEMBL14219716 | 0.90 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ATDP1MAP2K1 | |
| SCHEMBL14223049 | 0.90 | MAP2K1 (0.37) | ALDH1A1MEN1KMT2ATDP1MAP2K1 | |
| SCHEMBL14220117 | 0.85 | MEN1 (0.51) | MEN1KMT2ATDP1MAP2K1CSNK2A2 | |
| SCHEMBL14219743 | 0.84 | MEN1 (0.42) | ALDH1A1MEN1KMT2ATDP1MAP2K1 | |
| SCHEMBL14219843 | 0.84 | MAP2K1 (0.45) | MAP2K1CSNK2A2MAP2K2SMC2EGFR | |
| SCHEMBL14223052 | 0.84 | MAP2K1 (0.45) | MAP2K1CSNK2A2MAP2K2SMC2EGFR | |
| SCHEMBL14219656 | 0.83 | PTGS2 (0.41) | MEN1KMT2ATDP1MAP2K1CSNK2A2 | |
| SCHEMBL14223224 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL14219853 | 0.81 | MAP2K1 (0.40) | ALDH1A1MEN1KMT2ATDP1MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008041088-A2 | N-HYDROXY BENZAMIDES WITH ANTITUMOR ACTIVITY | EOS (ETHICAL ONCOLOGY SCIENCE) S.P.A. (IT) | 2008-04-10 | — | — | WO | disclosed |
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |