Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.56 |
| ▸ | CCKBR | P32239 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 14/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14290796 | 0.98 | ACLY (0.56) | ACLYCCKBRALDH1A1LMNAKDM4E | |
| SCHEMBL1422157 | 0.88 | ALDH1A1 (0.46) | ACLYCCKBRALDH1A1LMNAKDM4E | |
| SCHEMBL10238843 | 0.86 | ACLY (0.52) | ACLYCCKBRHTR6PKMSMN1; SMN2 | |
| SCHEMBL10239535 | 0.86 | ACLY (0.50) | ACLYCCKBRHTR6PKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9958211 | 0.85 | ACLY (0.52) | ACLYCCKBRHTR6PKMSMN1; SMN2 | |
| SCHEMBL10239558 | 0.85 | ACLY (0.52) | ACLYCCKBRHTR6 | |
| Hydrochloric Acid SCHEMBL9957918 | 0.85 | ACLY (0.49) | ACLYCCKBRHTR6PKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4523520 | 0.84 | ACLY (0.51) | ACLYCCKBRHTR6 | |
| SCHEMBL10240490 | 0.83 | ACLY (0.47) | ACLYCCKBRHTR6HTR2C | |
| Hydrochloric Acid SCHEMBL9958746 | 0.82 | ACLY (0.47) | ACLYCCKBRHTR6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297166-A1 | SUBSTITUTED N-IMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE DERIVATIVES AS 5-HT6 LIGANDS | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2011-03-23 | — | — | EP | claimed |