Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 10/20 | 0.55 |
| ▸ | MAP2K2 | P36507 | 8/20 | 0.55 |
| ▸ | DHODH | Q02127 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14222838 | 0.88 | MAP2K1 (0.57) | MAP2K1MAP2K2DHODHPIM1CAMK2B | |
| SCHEMBL14219621 | 0.88 | MAP2K1 (0.48) | MAP2K1MAP2K2DHODHLMNAGAA | |
| SCHEMBL14219608 | 0.86 | DHODH (0.54) | MAP2K1MAP2K2DHODHLMNAGAA | |
| SCHEMBL14220096 | 0.86 | MEN1 (0.40) | MAP2K1MAP2K2DHODHLMNAGAA | |
| SCHEMBL14219679 | 0.85 | MAP2K1 (0.46) | MAP2K1MAP2K2DHODHLMNAGAA | |
| SCHEMBL14219682 | 0.82 | MAP2K1 (0.44) | MAP2K1MAP2K2DHODHLMNAGAA | |
| SCHEMBL14219676 | 0.82 | MAP2K1 (0.40) | MAP2K1MAP2K2DHODHLMNAGAA | |
| SCHEMBL14219688 | 0.82 | LMNA (0.36) | MAP2K1MAP2K2DHODHLMNAGAA | |
| SCHEMBL29425477 | 0.79 | MAP2K1 (0.78) | MAP2K1MAP2K2PIM1CAMK2BIDO1 | |
| SCHEMBL4851710 | 0.79 | MAP2K1 (0.78) | MAP2K1MAP2K2PIM1CAMK2BIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008041088-A2 | N-HYDROXY BENZAMIDES WITH ANTITUMOR ACTIVITY | EOS (ETHICAL ONCOLOGY SCIENCE) S.P.A. (IT) | 2008-04-10 | — | — | WO | disclosed |
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |