SCHEMBL14219781

SCHEMBL14219781

O=C(OCCc1ccccc1)c1cccnc1

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.73
KMT2A Q03164 3/20 0.73
TDP1 Q9NUW8 2/20 0.73
L3MBTL1 Q9Y468 2/20 0.62
ESR1 P03372 1/20 0.59
ESR2 Q92731 1/20 0.59
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
MEN1 O00255 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
GPR52 Q9Y2T5 1/20 0.55
EPHX2 P34913 1/20 0.55
ALDH1A1 P00352 4/20 0.53
KDM4E B2RXH2 2/20 0.53
GAA P10253 1/20 0.53
PLOD2 O00469 1/20 0.51
MAPK1 P28482 1/20 0.51
MAPT P10636 1/20 0.51
USP2 O75604 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5363082 0.91 LMNA (0.71) LMNAKMT2ATDP1L3MBTL1MEN1
SCHEMBL25009812 0.89 L3MBTL1 (0.76) LMNAKMT2ATDP1L3MBTL1MEN1
SCHEMBL30556174 0.89 L3MBTL1 (0.76) LMNAKMT2ATDP1L3MBTL1MEN1
SCHEMBL25948348 0.88 LMNA (0.64) LMNAKMT2ATDP1L3MBTL1NPC1
SCHEMBL17978146 0.87 LMNA (0.65) LMNAKMT2ATDP1L3MBTL1MEN1
SCHEMBL25948396 0.85 KMT2A (0.61) LMNAKMT2ATDP1L3MBTL1NPC1
Benzyl Nicotinate SCHEMBL24600 0.84 LMNA (1.00) LMNAKMT2ATDP1L3MBTL1RAB9A
Benzyl Nicotinate SCHEMBL29394048 0.84 LMNA (1.00) LMNAKMT2ATDP1L3MBTL1RAB9A
SCHEMBL8407977 0.84 LMNA (0.62) LMNAKMT2ATDP1L3MBTL1NPC1
Phenethyl Benzoate SCHEMBL168823 0.84 ESR1 (0.80) LMNAKMT2ATDP1L3MBTL1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103497713-A Adhesive composition CORIUM INT INC 2014-01-08 CN disclosed
CN-103068385-A C5ar antagonists CHEMOCENTRYX INC 2013-04-24 CN disclosed
CN-102264227-A C5ar antagonists 2011-11-30 CN disclosed
EP-1911438-A2 Cosmetic composition containing a derivative of dibenzoylmethane and a arylalkyl amide or ester compound; method of photostabilising the derivative of dibenzoylmethane L'Oréal (FR) 2008-04-16 EP disclosed
US-20080019930-A1 Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds L'OREAL (FR) 2008-01-24 US disclosed
US-20080019930-A1 Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds L'OREAL (FR) 2008-01-24 US disclosed
CN-101039706-A Adhesive composition CORIUM INTERNAT INC (US) 2007-09-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080019930-A1 Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds TYR, DDT, AADAC LMNA 2641/4885KMT2A 1285/4885TDP1 2051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.