Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25948396 | 0.95 | KMT2A (0.61) | LMNAKMT2ATDP1L3MBTL1EPHX2 | |
| SCHEMBL14219781 | 0.88 | LMNA (0.73) | LMNAKMT2ATDP1L3MBTL1EPHX2 | |
| Nicoboxil SCHEMBL14917483 | 0.86 | TDP1 (0.70) | LMNAKMT2ATDP1L3MBTL1EPHX2 | |
| SCHEMBL5363082 | 0.84 | LMNA (0.71) | LMNAKMT2ATDP1L3MBTL1MEN1 | |
| SCHEMBL25945540 | 0.84 | LMNA (0.52) | LMNAKMT2ATDP1L3MBTL1EPHX2 | |
| SCHEMBL25329932 | 0.84 | L3MBTL1 (0.62) | LMNAKMT2ATDP1L3MBTL1MEN1 | |
| Nicoboxil SCHEMBL29475326 | 0.84 | L3MBTL1 (0.84) | LMNAKMT2ATDP1L3MBTL1MEN1 | |
| Nicoboxil SCHEMBL288321 | 0.84 | L3MBTL1 (0.84) | LMNAKMT2ATDP1L3MBTL1MEN1 | |
| SCHEMBL25330051 | 0.84 | LMNA (0.56) | LMNAKMT2ATDP1L3MBTL1MEN1 | |
| SCHEMBL25951686 | 0.83 | KMT2A (0.51) | LMNAKMT2ATDP1L3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147161-A2 | NICOTINATE AND NICOTINAMIDE RIBOSIDE-BASED COMPOUNDS AND DERIVATIVES THEREOF | New Frontier Bio, Inc. (US) | 2023-08-03 | — | — | WO | disclosed |