SCHEMBL14219979

SCHEMBL14219979

C/C=C/CCc1ccc(-c2ccc(CCC3CCC(C[C@H](C)c4ccccc4)CC3)cc2)cc1F

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14219351 1.00 HTR2A (0.30) HTR2AHTR2CKCNH2
SCHEMBL14219447 0.90 HTR2A (0.32) HTR2AHTR2C
SCHEMBL14219975 0.90
SCHEMBL14219433 0.90 HTR2A (0.32) HTR2AHTR2C
SCHEMBL14219476 0.88 DGAT1 (0.31)
SCHEMBL14219978 0.87 RARB (0.34) HTR2AHTR2C
SCHEMBL14219345 0.87 RARB (0.34) HTR2AHTR2C
SCHEMBL14219350 0.84 PDPK1 (0.35)
SCHEMBL14219485 0.83 FFAR4 (0.32)
SCHEMBL14219335 0.83 RORC (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1650285-B1 Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element SEIMI CHEM KK (JP) 2008-04-30 EP disclosed