SCHEMBL14219476

SCHEMBL14219476

C/C=C/CCc1ccc(-c2ccc(C3CCC(C[C@@H](C)c4ccccc4)CC3)cc2)cc1F

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 5/20 0.31
APP P05067 1/20 0.31
FFAR1 O14842 1/20 0.31
FFAR4 Q5NUL3 1/20 0.30
SOAT2 O75908 1/20 0.30
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14219485 0.90 FFAR4 (0.32) FFAR4
SCHEMBL14219606 0.89 RORC (0.31)
SCHEMBL14219335 0.89 RORC (0.31)
SCHEMBL14219323 0.89 RORC (0.31)
SCHEMBL14219423 0.89 DGAT1 (0.32) DGAT1APPFFAR1IDO1
SCHEMBL14219979 0.88 HTR2A (0.30)
SCHEMBL14219351 0.88 HTR2A (0.30)
SCHEMBL14219475 0.87 DGAT1 (0.33) DGAT1APPFFAR1SOAT2IDO1
SCHEMBL14219412 0.87 DGAT1 (0.33) DGAT1APPFFAR1SOAT2IDO1
SCHEMBL14219414 0.82 APP (0.37) DGAT1APPFFAR1SOAT2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1650285-B1 Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element SEIMI CHEM KK (JP) 2008-04-30 EP disclosed