SCHEMBL14220106 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	DHODH	Q02127	9/20	0.46

▸	CLCN2	P51788	3/20	0.38

▸	LMNA	P02545	1/20	0.36

▸	GAA	P10253	1/20	0.36

▸	EGFR	P00533	1/20	0.34

▸	SORT1	Q99523	1/20	0.33

▸	MAP2K1	Q02750	1/20	0.33

▸	PIK3CA	P42336	1/20	0.32

▸	MTOR	P42345	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14219812	0.88	DHODH (0.51)	DHODHCLCN2LMNAGAAEGFR
SCHEMBL14220139	0.88	NPC1 (0.38)	DHODHCLCN2LMNAGAAEGFR
SCHEMBL14219570	0.88	DHODH (0.48)	DHODHCLCN2LMNAGAAEGFR
SCHEMBL14219688	0.86	LMNA (0.36)	DHODHCLCN2LMNAGAAMAP2K1
SCHEMBL14219608	0.83	DHODH (0.54)	DHODHCLCN2LMNAGAAEGFR
SCHEMBL14219814	0.81	DHODH (0.43)	DHODHLMNAGAASORT1MAP2K1
SCHEMBL14219689	0.81	DHODH (0.39)	DHODHCLCN2LMNAGAAEGFR
SCHEMBL14219822	0.79	DHODH (0.38)	DHODHLMNAGAAMAP2K1
SCHEMBL14219683	0.78	LMNA (0.42)	DHODHCLCN2LMNAGAASORT1
SCHEMBL14222530	0.78	NPC1 (0.40)	DHODHLMNAGAASORT1MAP2K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1908751-A1	N-hydroxy benzamides with antitumour activity	EOS S.p.A. (IT)	2008-04-09	—	—	EP	disclosed