Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 12/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | SMC2 | O95347 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | SMC1A | Q14683 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.30 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14220178 | 0.90 | MAP2K1 (0.41) | MAP2K1MAP2K2ABCB11NQO2SMC2 | |
| SCHEMBL14220123 | 0.90 | MEN1 (0.35) | MAP2K1MEN1KMT2ATDP1LCK | |
| SCHEMBL14219832 | 0.89 | MEN1 (0.45) | MAP2K1MEN1KMT2ATDP1LCK | |
| SCHEMBL14220171 | 0.85 | MEN1 (0.41) | MAP2K1MEN1KMT2ATDP1DHODH | |
| SCHEMBL14220165 | 0.84 | MAP2K1 (0.41) | MAP2K1MEN1KMT2ATDP1DHODH | |
| SCHEMBL14223208 | 0.83 | MEN1 (0.43) | MAP2K1MEN1KMT2ATDP1DHODH | |
| SCHEMBL14220172 | 0.82 | DHODH (0.35) | MAP2K1MEN1KMT2ATDP1DHODH | |
| SCHEMBL14219684 | 0.82 | LMNA (0.42) | MEN1KMT2ALCKDHODHLMNA | |
| SCHEMBL14220162 | 0.82 | MAP2K1 (0.40) | MAP2K1MEN1KMT2ATDP1KDR | |
| SCHEMBL14219849 | 0.80 | MAP2K1 (0.43) | MAP2K1MAP2K2ABCB11NQO2SMC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |