Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 10/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219819 | 0.87 | DHODH (0.46) | LMNAGAADHODHMEN1KMT2A | |
| SCHEMBL14219683 | 0.85 | LMNA (0.42) | LMNAGAADHODHMEN1KMT2A | |
| SCHEMBL14220123 | 0.83 | MEN1 (0.35) | LMNAGAADHODHMEN1KMT2A | |
| SCHEMBL14220120 | 0.82 | MAP2K1 (0.36) | LMNAGAADHODHMEN1KMT2A | |
| SCHEMBL14219621 | 0.81 | MAP2K1 (0.48) | LMNAGAADHODHMEN1KMT2A | |
| SCHEMBL14220178 | 0.81 | MAP2K1 (0.41) | — | |
| SCHEMBL14222456 | 0.78 | DHODH (0.39) | LMNAGAADHODHCLCN2 | |
| SCHEMBL14219814 | 0.76 | DHODH (0.43) | LMNAGAADHODHMEN1KMT2A | |
| SCHEMBL14220139 | 0.75 | NPC1 (0.38) | LMNAGAADHODHMEN1KMT2A | |
| SCHEMBL14220096 | 0.75 | MEN1 (0.40) | LMNAGAADHODHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |