Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5914896 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HTTKDM4EGAAKMT2A | |
| SCHEMBL5914907 | 0.84 | ALDH1A1 (0.53) | ALDH1A1HTTKDM4EGAAKMT2A | |
| SCHEMBL7028753 | 0.82 | HIF1A (0.52) | ALDH1A1HTTKDM4EGAAKMT2A | |
| SCHEMBL8926817 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HTTKDM4EGAAKMT2A | |
| SCHEMBL6652101 | 0.70 | TSSK1B (0.48) | ALDH1A1HTTKDM4EGAAKMT2A | |
| SCHEMBL13016681 | 0.69 | ALDH1A1 (0.52) | ALDH1A1HTTKDM4EGAAKMT2A | |
| SCHEMBL31152138 | 0.69 | ALDH1A1 (0.83) | ALDH1A1HTTKDM4EGAAKMT2A | |
| SCHEMBL3775925 | 0.69 | ALDH1A1 (0.83) | ALDH1A1HTTKDM4EGAAKMT2A | |
| SCHEMBL6675540 | 0.69 | ALDH1A1 (0.57) | ALDH1A1HTTKDM4EGAAKMT2A | |
| SCHEMBL13016938 | 0.68 | ALDH1A1 (0.48) | ALDH1A1HTTKDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597263-B1 | PREPARATION OF A TRANS-CALANOLIDE KETONE INTERMEDIATE AND CHIRAL SEPARATION OF CALANOLIDE ALCOHOLS TO GIVE RACEMIC CALANOLIDE A | DOW GLOBAL TECHNOLOGIES INC (US) | 2008-04-23 | — | — | EP | disclosed |