SCHEMBL14220184

SCHEMBL14220184

C/C=C/CCc1ccc(C)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18364537 0.87
SCHEMBL19442949 0.86
SCHEMBL18364534 0.83
SCHEMBL17369450 0.83 RIPK1 (0.33)
SCHEMBL14211941 0.81 P2RX7 (0.32) P2RX7
SCHEMBL8232131 0.79 CTSS (0.36) P2RX7
SCHEMBL15316675 0.79
SCHEMBL19442909 0.78
SCHEMBL17487393 0.76 TYR (0.31)
SCHEMBL18375081 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1650284-B1 Liquid crystal composition containing an optical active compound and liquid crystal electro-optical element SEIMI CHEM KK (JP) 2008-04-30 EP disclosed