Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14204715 | 0.90 | DHODH (0.43) | ERN1MAOBGAAALDH1A1LMNA | |
| SCHEMBL14221547 | 0.84 | GAA (0.47) | MAOBGAAALDH1A1LMNAMAPT | |
| SCHEMBL14204719 | 0.80 | ERN1 (0.38) | ERN1MAOBGAAALDH1A1LMNA | |
| SCHEMBL13786667 | 0.79 | ALDH1A1 (0.48) | MAOBGAAALDH1A1LMNAMAPT | |
| SCHEMBL14204712 | 0.78 | ERN1 (0.58) | ERN1ALDH1A1CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL14206850 | 0.78 | GAA (0.52) | MAOBGAAALDH1A1LMNAMAPT | |
| SCHEMBL14035606 | 0.77 | GAA (0.46) | MAOBGAAALDH1A1LMNAMAPT | |
| SCHEMBL14221634 | 0.75 | MAOB (0.46) | MAOBGAAALDH1A1LMNAMAPT | |
| SCHEMBL13971251 | 0.74 | ALDH1A1 (0.47) | MAOBGAAALDH1A1LMNAMAPT | |
| SCHEMBL17547129 | 0.73 | LTA4H (0.64) | CYP1A2CYP19A1CYP2C9CYP2C19LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061238-A2 | PROCESSES FOR PRODUCTION OF 4-BIPHENYLYAZETIDIN-2-ONES | IRONWOOD PHARMACEUTICALS, INC. (US) | 2008-05-22 | — | — | WO | disclosed |