Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1422160 | 0.88 | ACLY (0.52) | ACLYCCKBRHTR6METADRA2A | |
| SCHEMBL1423427 | 0.81 | HTR6 (0.35) | ACLYNTRK1CCKBRHSD17B10POLB | |
| SCHEMBL1591782 | 0.76 | HTR6 (0.36) | POLBHTR6SMN1; SMN2 | |
| SCHEMBL1421917 | 0.70 | ALDH1A1 (0.47) | ACLYCCKBRHTR6SMN1; SMN2MET | |
| SCHEMBL1422189 | 0.70 | HTR6 (0.47) | HTR6PKMADRA2A | |
| SCHEMBL3868823 | 0.70 | TDP1 (0.44) | ACLYCCKBRHSD17B10HTR6SMN1; SMN2 | |
| SCHEMBL1422456 | 0.69 | ACLY (0.46) | ACLYCCKBRHTR6METADRA2A | |
| SCHEMBL1591157 | 0.69 | HTR6 (0.49) | POLBHTR6PKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1423306 | 0.69 | ACLY (0.45) | ACLYCCKBRHTR6METADRA2A | |
| SCHEMBL1423064 | 0.67 | TDP1 (0.44) | ACLYCCKBRPOLBHTR6MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297166-A1 | SUBSTITUTED N-IMIDAZO[2,1-B]THIAZOLE-5-SULFONAMIDE DERIVATIVES AS 5-HT6 LIGANDS | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2011-03-23 | — | — | EP | claimed |