SCHEMBL1422403

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1423475	0.85	NPC1 (0.63)	CHRNB2CHRNA5CHRNA4GRM5KCNH2
	SCHEMBL3611591	0.82	NOTUM (0.50)	CHRNB2CHRNA5CHRNA4GRM5KCNH2
	SCHEMBL4021783	0.81	CYP11B2 (0.56)	KCNH2CLK4NPY5RGABRG2GABRB3
	SCHEMBL1422881	0.81	CHRNB2 (0.90)	CHRNB2CHRNA5CHRNA4GRM5CLK4
	SCHEMBL2273610	0.80	CHRNB2 (0.67)	CHRNB2CHRNA5CHRNA4GRM5KCNH2
	SCHEMBL1422802	0.80	CHRNB2 (0.71)	CHRNB2CHRNA5CHRNA4GRM5SMN1; SMN2
	SCHEMBL4179248	0.79	GRM5 (0.65)	CHRNB2CHRNA5CHRNA4GRM5KCNH2
	SCHEMBL12371515	0.78	SMN1; SMN2 (0.46)	CHRNB2CHRNA5CHRNA4GRM5NPC1
	SCHEMBL18376891	0.77	NPC1 (0.65)	CHRNB2CHRNA5CHRNA4GRM5CLK4
	SCHEMBL1422531	0.77	CHRNB2 (0.59)	CHRNB2CHRNA5CHRNA4GRM5KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.