Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 5/20 | 0.55 |
| ▸ | TAOK3 | Q9H2K8 | 4/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12332426 | 0.95 | PLK1 (0.58) | TAOK1TAOK3PLK1HPGDTAS1R3 | |
| SCHEMBL15090036 | 0.84 | NPC1 (0.65) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15087731 | 0.84 | NPC1 (0.65) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15087819 | 0.84 | LMNA (0.51) | HPGDALDH1A1LMNANPSR1NPC1 | |
| SCHEMBL16373032 | 0.84 | NPC1 (0.65) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15087754 | 0.84 | HPGD (0.51) | HPGDNPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15087755 | 0.84 | EPHX2 (0.54) | HPGDNPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17208757 | 0.83 | PLK1 (0.59) | TAOK1TAOK3PLK1HPGDTAS1R3 | |
| SCHEMBL10268332 | 0.83 | HPGD (0.64) | TAOK1TAOK3PLK1HPGDTAS1R3 | |
| SCHEMBL5856001 | 0.81 | MLYCD (0.50) | HPGDALDH1A1NPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |