Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.46 |
| ▸ | PRF1 | P14222 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668334 | 0.95 | MPO (0.52) | HPGDNPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL15087731 | 0.87 | NPC1 (0.65) | HPGDNPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL15090036 | 0.87 | NPC1 (0.65) | HPGDNPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL16373032 | 0.87 | NPC1 (0.65) | HPGDNPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL15087755 | 0.87 | EPHX2 (0.54) | HPGDNPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL15087819 | 0.87 | LMNA (0.51) | HPGDNPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL14224151 | 0.84 | TAOK1 (0.55) | HPGDNPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL162726 | 0.82 | MLYCD (0.65) | HPGDNPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL24386356 | 0.81 | LMNA (0.56) | HPGDNPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL5800429 | 0.81 | LMNA (0.56) | HPGDNPC1RAB9ASMN1; SMN2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797946-B1 | SIALIC ACID DIMERS | BROSSMER REINHARD (DE) | 2016-05-04 | — | — | EP | disclosed |
| WO-2015128344-A1 | SIALIC ACID DERIVATIVES | BROSSMER REINHARD (DE) | 2015-09-03 | — | — | WO | disclosed |
| EP-2610263-A1 | Sialic acid dimers | Brossmer, Reinhard (DE) | 2013-07-03 | — | — | EP | disclosed |