Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924063 | 0.88 | ALDH1A1 (0.36) | GAATDP1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL14224631 | 0.88 | TDP1 (0.34) | TDP1KMT2ASMN1; SMN2 | |
| SCHEMBL4731399 | 0.83 | ALDH1A1 (0.38) | GAATDP1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL4733988 | 0.75 | KDM4E (0.40) | GAATDP1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL5156175 | 0.71 | MGLL (0.34) | — | |
| SCHEMBL509178 | 0.61 | MGLL (0.34) | — | |
| SCHEMBL12979105 | 0.60 | ALDH1A1 (0.46) | GAAKMT2A | |
| SCHEMBL14224627 | 0.60 | CYP11B1 (0.35) | — | |
| SCHEMBL14022449 | 0.59 | NPC1 (0.47) | KMT2ASMN1; SMN2 | |
| SCHEMBL24122988 | 0.56 | CYP3A4 (0.46) | GAATDP1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096950-A1 | Compounds Useful In Therapy | PFIZER INC. | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096950-A1 | Compounds Useful In Therapy | CYP19A1, LPXN, HSD17B11 | GAA 2843/4885TDP1 2204/4885HTT 4197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.