Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 12/20 | 0.42 |
| ▸ | NPC1 | O15118 | 11/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404165 | 0.91 | KDM4E (0.44) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16404149 | 0.88 | NPC1 (0.46) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16403932 | 0.88 | ALDH1A1 (0.45) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16404058 | 0.86 | SMN1; SMN2 (0.42) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16403964 | 0.86 | KDM4E (0.49) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16403922 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14684741 | 0.85 | ALDH1A1 (0.42) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16403989 | 0.85 | RAB9A (0.41) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16403991 | 0.85 | ALDH1A1 (0.40) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16403917 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |
| US-20120316148-A1 | Compositions and Methods for Modulating a Kinase | DYNAMIX PHARMACEUTICALS LTD. (IL) | 2012-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316148-A1 | Compositions and Methods for Modulating a Kinase | PRKCH, MAP3K2, MAP3K6 | KDM4E 2080/4885ALDH1A1 4672/4885RAB9A 3104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.