Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 11/20 | 0.52 |
| ▸ | CTSB | P07858 | 6/20 | 0.48 |
| ▸ | CTSL | P07711 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15670737 | 0.91 | CTSK (0.53) | SYKCTSKCTSBCTSLMAPT | |
| SCHEMBL15670736 | 0.91 | CTSK (0.53) | SYKCTSKCTSBCTSLMAPT | |
| SCHEMBL2061787 | 0.88 | SYK (0.55) | SYKCTSKCTSBCTSLPSMB1 | |
| SCHEMBL187066 | 0.88 | SYK (0.55) | SYKCTSKCTSBCTSLPSMB1 | |
| SCHEMBL2062558 | 0.88 | SYK (0.55) | SYKCTSKCTSBCTSLPSMB1 | |
| SCHEMBL20953619 | 0.88 | CTSK (0.55) | CTSKCTSBCTSLPSMB1PSMB5 | |
| SCHEMBL14285574 | 0.88 | CTSK (0.55) | CTSKCTSBCTSLPSMB1PSMB5 | |
| SCHEMBL141333 | 0.87 | SYK (0.49) | SYKCTSBCTSLMAPT | |
| SCHEMBL141332 | 0.87 | SYK (0.49) | SYKCTSBCTSLMAPT | |
| SCHEMBL995704 | 0.84 | SYK (0.56) | SYKCTSKCTSBCTSLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| EP-1140203-B1 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2007-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | SYK 4291/4885CTSK 1607/4885CTSB 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.