Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL141333 | 1.00 | SYK (0.49) | SYKCTSLMAPTMBOAT4CTSB | |
| SCHEMBL142265 | 0.87 | SYK (0.53) | SYKCTSLMAPTCTSB | |
| SCHEMBL115059 | 0.85 | CTSL (0.52) | CTSLCTSB | |
| SCHEMBL5971174 | 0.82 | PPARA (0.55) | SYKCTSLCTSBPPARA | |
| SCHEMBL2776833 | 0.82 | PPARA (0.55) | SYKCTSLCTSBPPARA | |
| SCHEMBL42877 | 0.82 | PPARA (0.55) | SYKCTSLCTSBPPARA | |
| SCHEMBL1555742 | 0.81 | SYK (0.57) | SYKCTSLMAPTCTSBPPARA | |
| SCHEMBL1555741 | 0.81 | SYK (0.57) | SYKCTSLMAPTCTSBPPARA | |
| SCHEMBL20346744 | 0.81 | KYNU (0.54) | SYKCTSLMAPTCTSBPPARA | |
| SCHEMBL21541316 | 0.81 | KYNU (0.54) | SYKCTSLMAPTCTSBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | SYK 4291/4885CTSL 1109/4885MAPT 4835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.