Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 3/20 | 0.57 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 11/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 11/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | OGT | O15294 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14226913 | 0.82 | STIM1 (0.63) | STIM1ORAI1KEAP1NFE2L2CA12 | |
| SCHEMBL10195868 | 0.79 | STIM1 (0.83) | STIM1ORAI1KEAP1NFE2L2CA12 | |
| SCHEMBL14226907 | 0.76 | KEAP1 (0.55) | STIM1ORAI1KEAP1NFE2L2CA12 | |
| SCHEMBL22643388 | 0.75 | KEAP1 (0.64) | STIM1ORAI1KEAP1NFE2L2CA12 | |
| SCHEMBL181689 | 0.75 | STIM1 (0.85) | STIM1ORAI1KEAP1NFE2L2CA12 | |
| SCHEMBL28940698 | 0.75 | KEAP1 (0.59) | STIM1ORAI1KEAP1NFE2L2CA12 | |
| SCHEMBL29626830 | 0.75 | KEAP1 (0.59) | STIM1ORAI1KEAP1NFE2L2CA12 | |
| SCHEMBL29946185 | 0.74 | STIM1 (0.86) | STIM1ORAI1KEAP1NFE2L2CA12 | |
| SCHEMBL26628275 | 0.74 | STIM1 (0.86) | STIM1ORAI1KEAP1NFE2L2CA12 | |
| SCHEMBL29727010 | 0.73 | OGT (0.66) | STIM1ORAI1KEAP1NFE2L2OGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895688-B2 | Halogen-free flame retarding materials based on bisphenol triazole resins and polymers | UNIVERSITY OF MASSCHUSETTS (US) | 2014-11-25 | — | — | US | disclosed |
| US-8895688-B2 | Halogen-free flame retarding materials based on bisphenol triazole resins and polymers | UNIVERSITY OF MASSCHUSETTS (US) | 2014-11-25 | — | — | US | disclosed |
| US-20120316313-A1 | HALOGEN-FREE FLAME RETARDING MATERIALS BASED ON BISPHENOL TRIAZOLE RESINS AND POLYMERS | UNIVERSITY OF MASSACHUSETTS | 2012-12-13 | — | — | US | disclosed |
| US-20120316313-A1 | HALOGEN-FREE FLAME RETARDING MATERIALS BASED ON BISPHENOL TRIAZOLE RESINS AND POLYMERS | UNIVERSITY OF MASSACHUSETTS | 2012-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316313-A1 | HALOGEN-FREE FLAME RETARDING MATERIALS BASED ON BISPHENOL TRIAZOLE RESINS AND POLYMERS | FFAR3, FHIT, BRPF3 | STIM1 4880/4885ORAI1 4873/4885KEAP1 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.