Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 10/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 10/20 | 0.55 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.48 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14226910 | 0.80 | PTGS2 (0.50) | NOTUMCYP1B1CA12CA1CA2 | |
| SCHEMBL14226916 | 0.76 | STIM1 (0.57) | KEAP1NFE2L2STIM1ORAI1HSD17B1 | |
| SCHEMBL15244877 | 0.75 | KEAP1 (0.55) | KEAP1NFE2L2STIM1ORAI1NOTUM | |
| SCHEMBL14226914 | 0.75 | ALDH1A1 (0.54) | KEAP1NFE2L2STIM1ORAI1NOTUM | |
| SCHEMBL16603465 | 0.73 | KEAP1 (0.55) | KEAP1NFE2L2STIM1ORAI1NOTUM | |
| SCHEMBL22643388 | 0.72 | KEAP1 (0.64) | KEAP1NFE2L2STIM1ORAI1NOTUM | |
| SCHEMBL29640061 | 0.72 | HSD17B1 (0.53) | KEAP1NFE2L2HSD17B1HSD17B2CA12 | |
| SCHEMBL28741924 | 0.72 | HSD17B1 (0.53) | KEAP1NFE2L2HSD17B1HSD17B2CA12 | |
| SCHEMBL1241813 | 0.72 | LMNA (0.73) | LMNA | |
| SCHEMBL15036886 | 0.72 | KEAP1 (0.48) | KEAP1NFE2L2STIM1ORAI1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895688-B2 | Halogen-free flame retarding materials based on bisphenol triazole resins and polymers | UNIVERSITY OF MASSCHUSETTS (US) | 2014-11-25 | — | — | US | disclosed |
| US-20120316313-A1 | HALOGEN-FREE FLAME RETARDING MATERIALS BASED ON BISPHENOL TRIAZOLE RESINS AND POLYMERS | UNIVERSITY OF MASSACHUSETTS | 2012-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316313-A1 | HALOGEN-FREE FLAME RETARDING MATERIALS BASED ON BISPHENOL TRIAZOLE RESINS AND POLYMERS | FFAR3, FHIT, BRPF3 | KEAP1 1265/4885NFE2L2 2377/4885STIM1 4880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.